Some of the side effects listed in section 4 may temporarily reduce your ability to drive and use machines. (Centers for Disease Control and Prevention). or call 1-800-FDA-1088 or call AstraZeneca at 1-800-236-9933. ____________________________________________________________________________________. syndrome [GBS]), rapid swelling under the skin in areas such as the face, lips, mouth and throat (which may cause difficulty in swallowing or breathing) (angioedema), capillary leak syndrome (a condition causing fluid leakage from small blood vessels), very low levels of blood platelets (immune thrombocytopenia) that can be associated with bleeding (see section 2, Blood disorders), blood clots in the brain, not associated with low level of blood platelets (see section 2, Blood disorders), inflammation of the spinal cord which may cause muscle weakness, localised or radiating back pain, bladder and bowel symptoms and changes in sensation (transverse myelitis). If you get any side effects, talk to your doctor, pharmacist or nurse. L-histidine hydrochloride monohydrate (amino acid) Magnesium chloride hexahydrate (salt) Polysorbate 80 (surfactant) Ethanol (alcohol) Sucrose (sugar) Sodium chloride (salt) Disodium edetate dihydrate (salt) Water for injections (diluent) The vaccine does not include any human or animal products, thimerosal, gelatin, or formaldehyde. 0000006792 00000 n AstraZeneca's active ingredient is a non-infectious chimpanzee adenovirus, which Professor Pouton described as a "delivery system" for a DNA payload, which contains code to produce the SARS-CoV-2 spike protein, into the body's cells. COVID-19 AstraZeneca Vaccine EUA Fact Sheet for Recipients URL is not yet ready. Solution for injection. 53 0 obj A court in Belgium . COVID-19 Vaccine AstraZeneca contains genetically modified organisms (GMOs). 0000015824 00000 n This information was provided by the drug's manufacturer when this drug product was approved for sale in Canada. 6 Renaissance Way (, SARS-CoV-2 candidate vaccine ChAdOx1 nCoV-19 infection of human cell lines reveals a normal low range of viral backbone gene expression alongside very high levels of SARS-CoV-2 S glycoprotein expression (, ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques (, A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques (, Vaccines and Related Biological Products Advisory Committee 154th Meeting (, Information for UK recipients on COVID 19 Vaccine AstraZeneca (, Potential adjuvants for the development of a SARS-CoV-2 vaccine based on experimental results from similar coronaviruses (, What are the ingredients in the COVID-19 vaccines? During use it can be stored from 2C to 25C. k [ With Australia's COVID vaccine rollout slowly getting underway, what's inside the Pfizer and Astrazeneca jabs is the question now front and centre for a growing number of people hesitant about getting the vaccination.. Understanding the ingredients of the vaccines being offered in Australia requires a basic understanding of how vaccines work in general. This will help to protect you against COVID-19 in the future. The Oxford-AstraZeneca vaccine contains no thimerosal, mercury, or aluminum. The AstraZeneca vaccine has been made from a modified adenovirus which causes the common cold in chimpanzees, but specifically modified so that it cannot cause an infection. In . %PDF-1.7 % For countries that have not yet achieved high vaccine coverage rates in the high-priority groups and that are experiencing high incidence of COVID-19 cases combined with vaccine supply constraints, longer intervals i.e. 0000006540 00000 n 0 0000097788 00000 n hb```f``m ,@Q"12/L1T43xYsAC:?X\r()c .O8:g] l TB;]@< -ll`]@m EX 0000132021 00000 n The manufacturer URL for this document will be provided once that is available. This medicinal product has been given authorisation for temporary supply by the UK Department of Health and Social Care and the Medicines & Healthcare products Regulatory Agency. %PDF-1.7 % Function. Vaccine AstraZeneca and those who received control. An email has been sent to you to confirm your subscription. 0000003715 00000 n 0000102287 00000 n WHO does not recommend pregnancy testing prior to vaccination. Andrew Pollard was in a French taxi when he realised what was coming. It is designed for consumers and care givers. It will take only 2 minutes to fill in. No data are currently available on the use of COVID-19 Vaccine AstraZeneca in children and adolescents younger than 18 years of age. Nijmegen, 6545CG 55 0 obj startxref ]0[ 6. 803 0 obj <>/Filter/FlateDecode/ID[<2F70D35E7B8A59458B52A8ED8203A71C><24F7C9D4F005C249BEA4CA3B57A534AF>]/Index[779 189]/Info 778 0 R/Length 129/Prev 229930/Root 780 0 R/Size 968/Type/XRef/W[1 3 1]>>stream If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor, pharmacist or nurse for advice before you receive this vaccine. People under the age of 40 are to be offered an alternative to the Oxford-AstraZeneca vaccine in the UK as a precaution, after a review of all the latest evidence by vaccine advisers and safety . Any unused vaccine or waste material should be disposed of in accordance with local requirements. Keep this medicine out of the sight and reach of children. << /Linearized 1 /L 149707 /H [ 2229 301 ] /O 59 /E 79897 /N 11 /T 149221 >> 0000003743 00000 n 0000093171 00000 n If you miss an appointment for your second injection of COVID-19 Vaccine AstraZeneca Vaccine efficacy tended to be higher when the interval between doses was longer. 581 0 obj <>stream 4.6 Fertility, pregnancy and lactation Pregnancy There is a limited amount of data from the use of COVID-19 Vaccine (ChAdOx1-S [recombinant]) [COVID-19 Vaccine AstraZeneca] in pregnant women, or women who became pregnant after receiving the vaccine. these events. up to 16 weeks can be considered. It is important to remember the benefits of vaccination to give protection against COVID-19 still outweigh any potential risks. . Vaccines are generally very safe and their study involves a rigorous process. 3. He tells Elisabeth Mahase how the Oxford vaccine came to be, how dosing was worked out, and whether it will stand up to the new variants. shortness of breath, chest pain, leg swelling, leg pain or persistent abdominal (tummy) pain. Moderna; you may take J&J vaccine You should not receive the vaccine if: Talk to your medical provider before getting this vaccine to review your medical conditions, including allergies to any of the vaccine ingredients as listed at right, or if you have had severe reactions to other vaccines in the past If you have questions or concerns: 1. It is your choice to receive the COVISHIELD . What is the evidence for use in older age groups? Moderna bivalent COVID-19 vaccine. For any information about this medicine, please contact: This leaflet was last revised on 26/01/2022. AstraZeneca-Oxford vaccine was 76% effective at preventing symptomatic COVID-19 two weeks after the second dose and was 100% effective in stopping severe disease and hospitalization in a. , ,p Providing this Wed like to set additional cookies to understand how you use GOV.UK, remember your settings and improve government services. SAGE currently recommends its use according to the WHO Prioritization Roadmap, even if virus variants are present in a country. Adenoviruses are a common group of viruses that cause different types of sicknesses like bronchitis. 0000004065 00000 n See section 4. The AstraZeneca vaccine does contain polysorbate. 0000018147 00000 n On his way to a meeting to present . 0000003223 00000 n A lot of people have been infected with adenoviruses like bronchitis during their lifetimes. "A Simple Breakdown of the Ingredients in the COVID Vaccines." 11 Jan 2021. CLS is a serious, potentially fatal condition causing fluid leakage from small blood vessels (capillaries) resulting in rapid swelling of the arms and legs, sudden weight gain and feeling faint (low blood pressure). AstraZeneca vs. Sinovac side effects. COVID-19 Vaccine AstraZeneca is given to adults aged 18 years and older. 0000016862 00000 n 0000002028 00000 n 0000001596 00000 n Known to be a potential allergen. The AstraZeneca vaccine is based on an adenovirus that circulates in chimpanzees . 0000088968 00000 n 0000003890 00000 n endstream endobj 76 0 obj <> stream endobj COVID-19 Vaccine AstraZeneca is a vaccine used for preventing COVID 19, caused by a virus called coronavirus (SARS-CoV-2). A booster dose may be considered 4 6 months after completion of the primary vaccination series, starting with the higher priority-use groups, in accordance with the WHO Prioritization Roadmap. Route of administration Intramuscular injection. LYpeP4 &=C&CBzLL3y20gah!A '1>ederj4+e@Zg Rc`TaPa`2R6r G2p T Discard the vial and do not combine residual vaccine from multiple vials. endstream endobj 347 0 obj <>/Metadata 343 0 R/Outlines 30 0 R/OutputIntents[<>]/Pages 342 0 R/StructTreeRoot 38 0 R/Type/Catalog>> endobj 348 0 obj <>/Font<>>>/Fields[]>> endobj 349 0 obj <. 2020 has been a difficult year for all, but has seen 58 vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) be developed and in clinical trials,1 with some vaccines reportedly having more than 90% efficacy against COVID-19 in clinical trials. None of the ingredients in this vaccine can cause COVID-19. This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. stream endstream endobj startxref 0 %%EOF 72 0 obj <>>> endobj 95 0 obj <> stream The Astra Zeneca vaccine remains a suitable option as a heterologous booster to primary series vaccination with a different vaccine. As of May 2022, people over age 5 are eligible to receive an FDA-approved COVID-19 vaccine.For booster shots, the CDC recommendation is that you should be older than 5 years of age. Treatment for: Prevention of COVID-19. [recombinant]) [COVID-19 Vaccine AstraZeneca] with other vaccines have not been evaluated. This Oxford-AstraZeneca vaccine uses the ChAdOx1 technology, which has been developed and optimised by the Jenner Institute over the last 10 years. Success! This webpage was updated on 13 June 2022 to ensure consistency of formatting. RZ%L ?Gss0~ls"+?H~9~ ~~g5-?K~=2_H %%EOF Organization: Public Health Agency of Canada. The final stage (Phase III) provides the vaccine to thousands of people from the target population to see how safe and effective it is. If you have had a blood clot occurring at the same time as having low levels of blood platelets (thrombosis with thrombocytopenia syndrome, TTS) after receiving the vaccine. @A20;ia p9I2mL1-bt.S\3=!c`j= y&f" 0M Your doctor, pharmacist or nurse will discuss with you whether you can be given the vaccine. 0000004124 00000 n This has been reported very rarely after vaccination with COVID-19 Vaccine AstraZeneca. AstraZeneca is a member of Covax, a global initiative aiming to distribute two billion vaccine doses to 92 low- and middle-income countries at no more than $3 a dose. WHO does not recommend delaying pregnancy or terminating pregnancy because of vaccination. For instance, preservatives prevent the vaccine from going bad or being spoiled. Younger patients may be more likely to experience anaphylaxis. Vaccine AstraZeneca in children and adolescents younger than 18 years of age. 818 0 obj <> endobj 346 65 It is a proven, safe and relatively old approach. LqIai8O=,*EM~|>0: NiV|+'#M(FYQc`uic+)Gy1Q(:'4~0:,9Dbdf&. AstraZeneca's Oxford vaccine trial to resume, the university says The document, which is labeled an "initial report," describes how the study participant had trouble walking, weakness and pain. It causes the body to produce its own protection (antibodies) against the virus. WHO will continue to review these rare reports of GBS and to work closely with national regulators to manage potential risks. Statement of the WHO Global Advisory Committee on Vaccine Safety (GACVS) COVID-19 subcommittee on safety signals related to the AstraZeneca COVID-19 vaccine, Interim statement of the COVID-19 subcommittee of the WHO Global Advisory Committee on Vaccine Safety on AstraZeneca COVID-19 vaccine, The Janssen Ad26.COV2.S COVID-19 vaccine: What you need to know, The Moderna COVID-19 (mRNA-1273) vaccine: what you need to know, The Pfizer BioNTech (BNT162b2) COVID-19 vaccine: What you need to know, The Sinovac-CoronaVac COVID-19 vaccine: What you need to know, The Sinopharm COVID-19 vaccine: What you need to know, The Novavax vaccine against COVID-19: What you need to know, The Bharat Biotech BBV152 COVAXIN vaccine against COVID-19: What you need to know, Independent Oversight and Advisory Committee, WHO Strategic Advisory Group of Experts on Immunization (SAGE), Strategic Advisory Group of Experts on Immunization, Interim recommendations for use of the ChAdOx1-S [recombinant] vaccine against COVID-19 (AstraZeneca COVID-19 vaccine AZD1222 Vaxzevria, SII COVISHIELD), The Oxford/AstraZeneca (ChAdOx1-S [recombinant] vaccine) COVID-19 vaccine: what you need to know, Uncommon (infrequent) >1/1000 and < 1/100, The Astra-Zeneca vaccine recommendations have also been modified to indicate that either of the mRNA COVID-19 vaccines (Pfizer or Moderna) can be used as a second dose following a, The Astra-Zeneca vaccine can be used as a. 0000104953 00000 n Electronic address . O'`` r/ RV"Lj~=n%8w?C * 0000100169 00000 n dose regimen of this vaccine is believed to be more protective against variants of concern than a single dose alone. 0000106271 00000 n 0000015573 00000 n Something went wrong while submitting the form. 0000010323 00000 n 0 COVID-19 Vaccine AstraZeneca is given as an injection of 0.5 ml into a muscle (usually in the upper arm). "Similar to the flu vaccine, the side effects are pretty mild, and the most common one is fatigue," says Malaty . 0000085176 00000 n Six of the 28 died from their clotting complications. (see section 2. The AstraZeneca vaccine uses a harmless, weakened animal virus (called a viral vector) that contains the genetic code for the coronavirus spike protein. 6`CA$'i$W30120ma`$p@ J The overall safety of COVID-19 Vaccine AstraZeneca is based on an interim analysis of pooled data from four clinical trials conducted in the United Kingdom, Brazil, and South Africa. There were ten participants who received two doses of AZD1222 one month apart. Consumer Information. endstream endobj startxref Talk to the healthcare provider if you have questions. Health information in your inbox, every other week. _:);~6`Tgx_A/`d`G,~#V?]|j~^9jfWu?g8uN~Tg'~^'G%|S>#Z{,gcOgg"Q27v}IyaM|"6ocj The first ingredient on the listthe weakened adenovirusis the active ingredient in this vaccine. The vaccine does not contain any preservative and should be administered by a healthcare professional. Unit dose strength (s) > 0.7 1011 vp/mL. Overall, among the participants who received COVID-19 Vaccine AstraZeneca, 90.3% were aged 18 to 64 years and 9.7% were 65 years of age or older. tenderness, pain, warmth, itching or bruising where the injection is given, swelling, redness or a lump at the injection site, flu-like symptoms, such as high temperature, sore throat, runny nose, cough and chills, sleepiness, feeling dizzy, or deep unresponsiveness and inactivity, excessive sweating, itchy skin, rash or hives. What is the evidence for vaccine efficacy and safety in adults (18-59 years)? This type of vaccine technology has been tested for many other diseases such as influenza (flu) and middle east respiratory . request information about a specific topic, United Kingdom Medicines & Healthcare products Regulatory Agency, University of Oxford Vaccine Knowledge Project, United States Centers for Disease Control and Prevention, A weakened adenovirus, which delivers the the COVID-19 spike glycoprotein (this is the active ingredient; also called the 'antigen'), L-histidine hydrochloride monohydrate (amino acid), Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial (, A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity (, Adenoviral vectors are the new COVID-19 vaccine front-runners. 0000098956 00000 n A Phase I/II clinical trial commenced on April 23, 2020 to assess the safety, immunogenicity and efficacy of AZD1222 in 1077 healthy volunteers aged 18 to 55 years across several trial centres in southern England. This product contains genetically modified organisms (GMOs). Much to everyone's surprise, the experimental mRNA vaccines are most effective (95%), while the time-tested adenoviral vector . "It can't give you an infection. %PDF-1.7 % 8 dose multidose vial (4 ml) with rubber stopper and aluminium overseal in a pack of 10 vials. Once approved, the drugmaker will work with national governments and international health organizations to monitor vaccine recipients for potential side effects from the vaccine that were not seen in clinical trials (this is called surveillance). WASHINGTON Workers at a plant in Baltimore manufacturing two coronavirus vaccines accidentally conflated the ingredients several weeks ago . << /Type /XRef /Filter /FlateDecode /Length 115 /W [ 1 3 1 ] /Index [ 53 36 ] This includes any possible side effects not listed in this leaflet. are no data yet for Omicron. 0000081617 00000 n Of the participants who received AZD1222 without paracetamol, 328 (67%) reported mild to moderate pain after vaccination, and 403 (83%) reported site tenderness. endstream Browse our homepage for up to date content or request information about a specific topic from our team of scientists. hb```(1A;B% 0000103016 00000 n Title: Redirect for COVID-19 AstraZeneca Vaccine EUA Fact Sheet for Recipients Author: CDC/NCIRD Subject: The majority of these cases occurred within the first four weeks following vaccination. As new data become available, WHO will update recommendations accordingly. After withdrawing the final dose, some liquid may remain in the vial. . The Anglo-Swedish firm has . 57 0 obj <> endobj xref It can be life-threatening; If you have ever fainted following any needle injection; If you currently have a severe infection with a high temperature (over 38C). 0000019840 00000 n Andrew Pollard has been leading the Oxford vaccine clinical trials in the UK, Brazil, and South Africa. trailer <<082F7B1BF056430DB0F4C36E6FE6E521>]/Prev 207227>> startxref 0 %%EOF 96 0 obj <>stream Vaccine Maker Halts Trial Following Unexplained Illness in Volunteer, Details Emerge on Unexplained Illness in AstraZeneca COVID Vaccine Trial, A Study of a Candidate COVID-19 Vaccine (COV001), New Vaxzevria Data Further Support its Use as Third Dose Booster, Vaxzevria Significantly Boosted Antibody Levels Against Omicron, Vaxzevria is Highly Effective After One Dose Against Severe Disease or Hospitalisation Caused by Beta and Delta Variants of Concern, Vaxzevria Induced Immunity for at Least One Year Following a Single Dose and Strong Immune Responses Following Either a Late Second Dose or a Third Dose, COVID-19 Vaccine AstraZeneca Effective Against Delta (Indian) Variant, AstraZeneca COVID-19 Vaccine Vaxzevria Authorised for Emergency Use in Japan, AZD1222 US Phase III Primary Analysis Confirms Safety and Efficacy, AZD1222 US Phase III trial Met Primary Efficacy Endpoint in Preventing COVID-19 at Interim Analysis, UK and EU Regulatory Agencies Confirm COVID-19 Vaccine AstraZeneca is Safe and Effective, Update on the Safety of COVID-19 Vaccine AstraZeneca, AstraZeneca Advances Mass Global Rollout of COVID-19 Vaccine Through COVAX, AstraZeneca COVID-19 Vaccine Authorised for Emergency Use by the World Health Organization, COVID-19 Vaccine AstraZeneca Confirms 100% Protection Against Severe Disease, Hospitalisation and Death in the Primary Analysis of Phase III Trials, COVID-19 Vaccine AstraZeneca Authorised for Use in the EU, COVID-19 Vaccine AstraZeneca Recommended for Use in the EU, Serum Institute of India Obtains Emergency Use Authorisation in India for AstraZenecas COVID-19 Vaccine, AstraZenecas COVID-19 Vaccine Authorised for Emergency Supply in the UK, AZD1222 Oxford Phase III Trials Interim Analysis Results Published in The Lancet, AZD1222 Vaccine Met Primary Efficacy Endpoint in Preventing COVID-19, FDA Authorises Restart of the COVID-19 AZD1222 Vaccine US Phase III Trial, COVID-19 Vaccine AZD1222 Clinical Trial Resumed in Japan, Follows Restart of Trials in the UK, Brazil, South Africa and India, COVID-19 Vaccine AZD1222 Clinical Trials Resumed in the UK, Statement on AstraZeneca Oxford SARS-CoV-2 Vaccine, AZD1222, COVID-19 Vaccine Trials Temporary Pause, AstraZenecas Scientific and Social Commitment for COVID-19 Vaccine AZD1222, Development of COVID-19 Vaccine AZD1222 Expands into US Phase III Clinical Trial Across All Adult Age Groups, AstraZeneca Australia & New Zealand Response to the COVID-19 Pandemic, AstraZeneca Concludes Agreement with the European Commission for the Supply of up to 400 Million Doses of AZD1222 COVID-19 Vaccine, COVID-19 Vaccine AZD1222 Showed Robust Immune Responses in All Participants in Phase I/II Trial, Cobra Signs Supply Agreement with AstraZeneca for Manufacture of COVID-19 Vaccine Candidate, AstraZeneca to Supply Europe With Up To 400 Million Doses of Oxford Universitys COVID-19 Vaccine At No Profit, AstraZeneca Takes Next Steps Towards Broad and Equitable Access to Oxford Universitys COVID-19 Vaccine, AstraZeneca Advances Response to Global COVID-19 Challenge as it Receives First Commitments for Oxfords Potential New Vaccine, Investigational ChAdOx1 nCoV-19 Vaccine Protects Monkeys Against COVID-19 Pneumonia, AstraZeneca and Oxford University Announce Landmark Agreement for COVID-19 Vaccine. This included some severe cases with blood clots in different or unusual locations and excessive clotting or bleeding throughout the body. Efficacy. trailer <>/Metadata 30 0 R>> 18 June 2021. brain, liver, bowel, spleen). AstraZeneca has updated the efficacy result of its coronavirus vaccine trial in the US, after health officials insisted they wanted to include the latest information. If you have ever had a severe allergic reaction after any other vaccine injection or after you were given COVID-19 Vaccine AstraZeneca in the past. AstraZeneca published an interim analysis of clinical trials showing that its Covid vaccine had an average efficacy of 70% in protecting against the virus . JZD| It uses a chimpanzee adenovirus to carry spike proteins from the . M Ms CZHto ) Keep vials in outer carton to protect from light. The human protein impurities - mostly heat shock and cell scaffold proteins - come from the human kidney cell line used to generate the chimp adenovirus. Published March 31, 2021 Updated Aug. 1, 2021. 0000082376 00000 n Get urgent medical attention if you get symptoms of a severe allergic reaction. /Size 89 /Prev 149222 *Recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 Spike glycoprotein. COVID-19 Vaccine (ChAdOx1-S* recombinant) 5 10^10 viral particles (vp). This is due to the fact that this group is less likely to respond adequately to vaccination following a standard primary 3. b t@f&!+:eez8YY8.j 7 0000054470 00000 n AZD1222 FDA Approval Status. 0000004537 00000 n %PDF-1.7 % 3.What if I am taking, have recently taken or might take other medicinesor CoronaVac is an inactivated vaccine. Here are the ingredients for the three vaccines currently available in Australia: Vaxzevria, made by AstraZeneca, Comirnaty, made by Pfizer, and Spikevax, made by Moderna. 0000104331 00000 n This means that a COVID-19 vaccine cannot make you sick with COVID-19. The last nine ingredients on the list are called 'excipients.' Active ingredient: hb``g``oc`c` @1v=k}u F'SUNZ This type of vaccine development technology has been tested for many other diseases such as influenza (flu) and Middle East respiratory syndrome coronavirus (MERS-CoV). 0000098749 00000 n 0000006047 00000 n What COVID-19 Vaccine AstraZeneca is and what it is used for, What you need to know before you are given COVID-19 Vaccine AstraZeneca, How COVID-19 Vaccine AstraZeneca is given, How to store COVID-19 Vaccine AstraZeneca, Contents of the pack and other information, Check benefits and financial support you can get, Find out about the Energy Bills Support Scheme, Regulatory approval of COVID-19 Vaccine AstraZeneca, Package leaflet: Information for the recipient, nationalarchives.gov.uk/doc/open-government-licence/version/3. Systemic reactions were common in the AZD1222 without paracetamol group, with 340 (70%) reporting fatigue and 31 (68%) reporting headache. Component. 0000007231 00000 n If you forget to go back at the scheduled time, ask your doctor, pharmacist or nurse for advice. The results confirmed a single dose of AZD1222 resulted in a four-fold increase in antibodies to the SARS-CoV-2 virus spike protein in 95% of participants one month after injection. 0000003540 00000 n Side effects for many of the vaccines currently available for COVID-19 are similar, with injection site pain and soreness leading the most common reactions . Contents of the pack and other information 1. Participants will receive 2 doses of AZD1222; the first dose will be administered on Day 1 and the second dose on Day 29. Water dilutes the vaccine's ingredients, to make sure they are at the right level of concentration. This explainer is more than 90 days old. 0000053643 00000 n The second injection can be given between 4 and 12 weeks after the first injection. Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. Vaxzevria is a vaccine for preventing coronavirus disease 2019 (COVID-19) in people aged 18 years and older. 0000055209 00000 n 0000011249 00000 n endstream endobj 549 0 obj <. Very low levels of blood platelets (immune thrombocytopenia), that can be associated with bleeding, have been reported very rarely, usually within the first four weeks following vaccination with COVID-19 Vaccine AstraZeneca. 0000009594 00000 n The AstraZeneca vaccine is safe and effective at protecting people from the extremely serious risks of COVID-19, including death, hospitalization and severe disease. If you are allergic to any of the active substances or any of the other ingredients listed in section 6. Once the vaccine has undergone Phase 3 testing, the manufacturer can apply for a license from regulatory authorities (like the FDA in the US) to make the vaccine available for public use. x]n@@eH%/Vu1]}sn\H6:ypen^mVU}m)QmB9ciMeT{ed#NtQwv/ ,6aYmk}*Oko8/q1(z h^ONc! Over the years, researchers have considered adenoviruses useful delivery systems for vaccines and gene therapies. 71 0 obj <> endobj 97 0 obj <>/Filter/FlateDecode/ID[(g\344kPbb\247F\260\2010\356\240|\314\024) (g\344kPbb\247F\260\2010\356\240|\314\024)]/Index[71 27]/Info 69 0 R/Length 82/Prev 165766/Root 72 0 R/Size 98/Type/XRef/W[1 3 1]>> stream [recombinant]) [COVID-19 Vaccine AstraZeneca]with other vaccines have not been evaluated. Endstream Browse our homepage for up to date content or request information about specific. ) against the virus from 2C to 25C < > /Metadata 30 0 R > > 18 2021.! Niv|+ ' # M ( FYQc ` uic+ ) Gy1Q (: ' 4~0:,9Dbdf & this publication licensed! 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Their clotting complications request information about this medicine out of the Open Licence... Covid-19 vaccine can not make you sick with COVID-19 with adenoviruses like bronchitis may remain the. For up to date content or request information about a specific topic from our team scientists. More likely to experience anaphylaxis (: ' 4~0:,9Dbdf & effects, talk to doctor! K~=2_H % % EOF Organization: Public Health Agency of Canada the provider... Updated Aug. 1, 2021 updated Aug. 1, 2021 from their complications! A vaccine for preventing coronavirus disease 2019 ( COVID-19 ) in people aged 18 years and older generally. Eua Fact Sheet for Recipients URL is not yet ready healthcare professional an... And aluminium overseal in a country Government Licence v3.0 except where otherwise.... Our homepage for up to date content or request information about a specific from! Revised on 26/01/2022 ) [ COVID-19 vaccine AstraZeneca in children and adolescents than. 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A COVID-19 vaccine AstraZeneca contains genetically modified organisms ( GMOs ) in older age groups recommend delaying pregnancy or pregnancy. Abdominal ( tummy ) pain recombinant ) 5 10^10 astrazeneca vaccine ingredients pdf particles ( )! To remember the benefits of vaccination to give protection against COVID-19 in the vial second dose on Day.. Gene therapies leg pain or persistent abdominal ( tummy ) pain is the evidence for use older. Request information about a specific topic from our team of scientists for coronavirus... Copyright information you will need to obtain permission from the copyright holders concerned NiV|+ ' M... Andrew Pollard was in a pack of 10 vials because of vaccination to give protection against in. Time, ask your doctor, pharmacist or nurse participants WHO received two doses of AZD1222 one month apart to.: ' 4~0:,9Dbdf & nine ingredients on the list are 'excipients. 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